Closed-loop neural stimulation for pentylenetetrazole-induced seizures in zebrafish
SUMMARY Neural stimulation can reduce the frequency of seizures in persons with epilepsy, but Queen LP Foundation rates of seizure-free outcome are low.Vagus nerve stimulation prevents seizures by continuously activating noradrenergic projections from the brainstem to the cortex.Cortical norepinephrine then increases GABAergic transmission and incr